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Bioanalytical Assay List

BioPharma Services has completed a wide range of Bioanalytical Assays in various biological matrices.

The methods tabulated below vary from Qualified to Fully Validated Methods.

Bioanalytical Assays are critical for drug development, where they are used to measure the safety and efficacy of potential new treatments. In clinical research, they can be used to monitor disease progression and the effectiveness of therapies. In diagnostic applications, they can identify biomarkers that can be used to detect or monitor disease.

Bioanalytical Assays are essential for measuring biological molecules in a wide range of applications, including drug development, clinical research, and disease diagnosis. By viewing our Bioanalytical Assays, you can save valuable time and resources, no longer having to search for different service providers or wait for quotes from multiple vendors.

Our Bioanalytical Assays use a variety of techniques to detect and quantify molecules such as proteins, peptides, nucleic acids, and metabolites in biological samples. BioPharma Services’ Bioanalytical Assays offer an efficient, streamlined and transparent process for the drug sponsor to access the necessary analytical services for their drug development projects.

List of Validated LC-MS/MS Bioanalytical Methods

Analyte(s)MatrixAnticoagulantLLOQ
1-AminoindanHuman Plasma20 pg/mLK2EDTA
AbirateroneHuman Plasma0.2 ng/mLK2EDTA
Acalabrutinib/Metabolite M27Human Plasma1/1 ng/mLK2EDTA
AcetaminophenHuman Plasma75 ng/mLK2EDTA
Acetaminophen (with Tramadol)Human Plasma75 ng/mLK2EDTA
Acetylsalicylic AcidHuman Plasma2.5 ng/mLSodium Fluoride/Potassium Oxalate
Albendazole/Albendazole Sulfoxide (LR)Human Plasma0.1/1 ng/mLK2EDTA
AmbrisentanHuman Plasma50 ng/mLK2EDTA
AmifampridineHuman Plasma150 pg/mLK2EDTA
AmlodipineHuman Plasma5 pg/mLK2EDTA
Amlodipine (with Lisinopril)Human Plasma0.15 ng/mLK2EDTA
Amphetamine (D/L) ChiralHuman Plasma0.2/0.2 ng/mLK2EDTA
Amphetamine (D/L) ChiralHuman Plasma50 /50 pg/mLK2EDTA
ApalutamideHuman Plasma5 ng/mLK2EDTA
ApixabanHuman Plasma1 ng/mLK2EDTA
ApomorphineHuman Plasma50 pg/mLK2EDTA
AprepitantHuman Plasma25 ng/mLK2EDTA
AripiprazoleHuman Plasma0.2 ng/mLK2EDTA
Atorvastatin and Ezitimibe (free)Human Plasma100/50 ng/mLK2EDTA
Atovaquone (with Proguanil)Human Plasma25 ng/mLK2EDTA
AxitinibHuman Plasma0.5 ng/mLK2EDTA
Axitinib (LR)Human Plasma0.25 ng/mLK2EDTA
AzithromycinHuman Plasma1 ng/mLK2EDTA
AzilsartanHuman Plasma50 ng/mLK2EDTA
Bempedoic AcidHuman Plasma100/10 ng/mLK2EDTA
Bempedoic Acid and Metabolite ESP15228Human Plasma100/10 ng/mLK2EDTA
BexaroteneHuman Plasma1 ng/mLK2EDTA
BisoprololHuman Plasma0.2 ng/mLK2EDTA
BromazepamHunam Plasma1 ng/mLK2EDTA
BudesonideHuman Plasma3 pg/mLNaF/K-Oxalate
BudesonideHuman Plasma50 pg/mLNaF/K-Oxalate
BudesonideHuman Plasma100 pg/mLNaF/K-Oxalate
BuprenorphineHuman Plasma1 pg/mLK2EDTA
Buprenorphine/Norbuprenorphine (with Naloxone)Human Plasma25/20 pg/mLK3EDTA
Carglumic Acid (high range)Human Plasma25 ng/mLSodium Heparin
Carglumic Acid (low range)Human Plasma10 ng/mLSodium Heparin
CariprazineHuman Plasma10 pg/mLK2EDTA
CBD (with THC & 11-OH-THC)Human Plasma50 pg/mLK2EDTA
CefiximeHuman Plasma50 ng/mLK2EDTA
CelecoxibDog Plasma1 ng/mLK3EDTA
CelecoxibDog Synovial Fluid1 ng/mLK3EDTA
CelecoxibRat Plasma1 ng/mLK3EDTA
CelecoxibHuman Plasma1 ng/mLK2EDTA
Chlorphenamine Maleate (Chiral)Human Plasma50/50 pg/mLK2EDTA
ChlorzoxazoneHuman Plasma0.1 µg/mLK2EDTA
CiprofloxacinHuman Plasma10 ng/mLK2EDTA
CitalopramHuman Plasma0.5 ng/mLK2EDTA
ClindamycinHuman Plasma25 ng/mLK2EDTA
Clobazam/N-DesmethyclobazamHuman Plasma1/0.35 ng/mLK2EDTA
Clobazam/N-DesmethyclobazamHuman Plasma1/3 ng/mLK2EDTA
Clobetasol PropionateHuman Plasma40 pg/mLK2EDTA
ClonidineHuman Plasma10 pg/mLK2EDTA
CysteamineHuman Plasma20 ng/mLSodium Heparin
Dabigatran (free)Human Plasma1 ng/mLK2EDTA
Dabigatran (total)Human Plasma1 ng/mLK2EDTA
DapsoneHuman Plasma5 ng/mLSodium Fluoride/Potassium Oxalate
DasatinibHuman Plasma1 ng/mLK2EDTA
DeferasiroxHuman Plasma40 ng/mLK2EDTA
DeferiproneHuman Serum50 ng/mLN/A
DesoximetasoneHuman Plasma25 pg/mLK2EDTA
DexamethasoneHuman Plasma0.3 ng/mLK2EDTA
DexlansoprazoleHuman Plasma1 ng/mLK2EDTA
DexmethylphenidateHuman Plasma100 pg/mLSodium Fluoride/Potassium Oxalate
DiazepamHuman Plasma5 ng/mLK2EDTA
DichlorphenamideHuman Plasma1 ng/mLK2EDTA
DicyclomineHuman Plasma0.3 ng/mLK2EDTA
DienogestHuman Plasma1 ng/mLK2EDTA
DipyridamoleHuman Plasma7 ng/mLK2EDTA
Dofetilide (with Mexiletine)Human Plasma20 pg/mL/ 3 ng/mLK2EDTA
Dolutegravir (with Lamotrigine and Tenofovir)Human Plasma20 ng/mLK2EDTA
DonepezilHuman Plasma100 pg/mLK2EDTA
Doxepine/Nordoxepin (High Range)Human Plasma100/100 pg/mLK2EDTA
Doxepine/Nordoxepin (Low Range)Human Plasma25/25 pg/mLK2EDTA
DoxycyclineHuman Plasma20 ng/mLK2EDTA
Doxylamine (qualified method)Human Plasma0.25 ng/mLK2EDTA
DroxidopaHuman Plasma10 ng/mLK2EDTA
DutasterideHuman Plasma30 pg/mLK2EDTA
Edaravone (free)Human Plasma2 ng/mLK2EDTA
Edaravone Sulfate/Edaravone GlucuronideHuman Plasma5/2 ng/mLK2EDTA
EfavirenzHuman Plasma10 ng/mLK2EDTA
ElagolixHuman Plasma5 ng/mLK2EDTA
EmpagliflozinHuman Plasma0.5 ng/mLK2EDTA
EmtricitabineHuman Plasma10 ng/mLK2EDTA
EnzalutamideHuman Plasma510 ng/mLK2EDTA
Eplerenone (with Furosemide)Human Plasma15 ng/mLK2EDTA
ErlotinibHuman Plasma5 ng/mLK2EDTA
EsomeprazoleHuman Plasma1.5 ng/mLK2EDTA
Ethacrynic AcidHuman Plasma0.5 pg/mLK2EDTA
Ethinyl Estradiol (with Norethindrone)Human Plasma1 pg/mLK2EDTA
EverolimusWhole Blood0.2 ng/mLK2EDTA
Ezetimibe (total)Human Plasma0.2 ng/mLK2EDTA
EzogabineHuman Plasma5 ng/mLK2EDTA
Fesoterodine/5-HMTHuman CSF2/2 pg/mLN/A
Fesoterodine/5-HMTHuman Urine2/10 pg/mLN/A
FelbamateDog Plasma200 ng/mLK2EDTA
FelbamateHuman Plasma200 ng/mLK2EDTA
FinasterideHuman Plasma0.5 pg/mLK2EDTA
FingolimodWhole Blood5 pg/mLK2EDTA
Fingolimod PhosphateWhole Blood25 pg/mLK2EDTA
FlecainideHuman Plasma0.8 ng/mLK2EDTA
FluconazoleHuman Plasma50 ng/mLK2EDTA
Fluticasone FuroateHuman Plasma0.5 pg/mLK3EDTA
Fluticasone PropionateHuman Plasma1 pg/mLK2EDTA
Fluticasone Propionate (with Salmeterol)Human Plasma1 pg/mLK2EDTA
FormoterolHuman Plasma0.3 pg/mLSodium Fluoride/Potassium Oxalate
Furosemide (with Eplerenone)Human Plasma15 ng/mLK2EDTA
GabapentinHuman Plasma10 ng/mLK2EDTA
Gamma Hydroxybutyrate (GHB)Human Plasma0.5 µg/mLK2EDTA
GefitinibHuman Plasma1 ng/mLK2EDTA
Gepirone and MetabolitesHuman Plasma20/20/20 pg/mLK2EDTA
Gepirone and MetabolitesHuman Plasma40/100/40 pg/mLK2EDTA
Gamma Hydroxybutyrate (GHB)Human Plasma0.5 µg/mLNaF/K-Oxalate
GepironeHuman Plasma20/20/20 pg/mLK2EDTA
GliclazideHuman Plasma5 ng/mLK2EDTA
GliclazideHuman Plasma25 ng/mLK2EDTA
HydrocodoneHuman Plasma0.1 ng/mLK2EDTA
HydroxychloroquineHuman Whole Blood2 ng/mLSodium Heparin
Hydroxymethyl Tolterodine (5HMT)Human Plasma20 pg/mLK2EDTA
Ibrutinib (High Range)Human Plasma1.50 ng/mLK2EDTA
Ibrutinib (Low Range)Human Plasma0.5 ng/mLK2EDTA
IbuprofenHuman Plasma100 ng/mLK2EDTA
IdelalisibHuman Plasma10 ng/mLK2EDTA
Imatinib/N-Desmethyl ImatinibHuman Plasma10/2 ng/mLK2EDTA
IndapamideHuman Whole Blood0.25 ng/mLK2EDTA
IvabradineHuman Plasma100/10 pg/mLK2EDTA
Ivabradine/N-Desmethyl IvabradineHuman Plasma100/10 pg/mLK2EDTA
Ivacaftor/Lumacaftor (VX-809)Human Plasma3/40 ng/mLK2EDTA
Ketamine/NorketamineHuman Plasma0.4/4 ng/mLK2EDTA
LacosamideHuman Plasma100 ng/mLK2EDTA
Lamivudine (with Dolutegravir & Tenofovir)Human Plasma50 ng/mLK2EDTA
LamotrigineHuman Plasma10 ng/mLK2EDTA
LansoprazoleHuman Plasma1 ng/mLK2EDTA
LenalidomideHuman Plasma1 ng/mLK2EDTA
LenvatinibHuman Plasma0.5 ng/mLK2EDTA
LeuprolideHuman Plasma50 pg/mLK2EDTA
LevetiracetamHuman Plasma0.2 µg/mLK2EDTA
LevetiracetamHuman Plasma50 ng/mLK2EDTA
LevomilnacipranHuman Plasma1 ng/mLK2EDTA
LevothyroxineHuman Serum10 ng/mLN/A
Lidocaine (with Prilocaine)Human Plasma100 pg/mLK2EDTA
Liraglutide Human Plasma1 ng/mL K2EDTA
Lisdexamfetamine/D-AmphetamineHuman Plasma0.4/0.8 ng/mLK2EDTA
Lisinopril (with Amlodipine)Human Plasma1.5 ng/mLK2EDTA
Loxapine/7 and 8-Hydroxy LoxapineHuman Plasma10/10/10 pg/mLK2EDTA
MacitentanHuman Plasma1 ng/mLK2EDTA
MesalamineHuman Plasma2 ng/mLK2EDTA
MetforminHuman Plasma6 ng/mLK2EDTA
MethylnaltrexoneHuman Plasma0.1 ng/mLK2EDTA
MethylphenidateHuman Plasma20 pg/mLSodium Fluoride/Potassium Oxalate
MethylphenidateHuman Plasma100 pg/mLSodium Fluoride/Potassium Oxalate
MetolazoneHuman Plasma0.5 ng/mLK2EDTA
MetoprololHuman Plasma0.6 ng/mLK2EDTA
Mexiletine (with Dofetilide)Human Plasma3 ng/mLK2EDTA
Midazolam/Alpha-HydroxymidazolamHuman Plasma1/0.5 ng/mLK2EDTA
Midostaurin/CGP62221/CGP52421Human Plasma7.5/5/5 ng/mLK2EDTA
MirtazapineHuman Plasma0.25 ng/mLK2EDTA
ML-007Human CSF1 ng/mLN/A
Mometasone FurorateHuman Plasma0.5 pg/mLK3EDTA
Monomethyl FumarateHuman Plasma25 ng/mLSodium Fluoride/Potassium Oxalate
Morphine/Morphine 6-GlucuronideHuman Plasma0.2/0.4 ng/mLK2EDTA
Naloxone (Free)Human Urine0.4 ng/mLN/A
Naloxone (Free) (with Buprenorphine and Norbuprenorphine)Human Plasma3 pg/mLK2EDTA
Naloxone (with Oxycodone)Human Plasma1 pg/mLK2EDTA
Naloxone-3 β D glucoronideHuman Plasma50 pg/mLK3EDTA
Naltrexone/6β-Naltrexol (High Range)Human Plasma20/20 pg/mLK2EDTA
Naltrexone/6β-Naltrexol (Low Range)Human Plasma0.5/0.5 pg/mLK2EDTA
NebivololHuman Plasma100 pg/mLK2EDTA
NeratinibHuman Plasma50 pg/mLK2EDTA
Nicotine/CotinineHuman Plasma0.2/2 ng/mLK2EDTA
NifedipineHuman Plasma0.1 ng/mLK2EDTA
NirmatrelvirHuman Plasma25 ng/mLK2EDTA
NitrofurantoinHuman Plasma0.2 ng/mLK2EDTA
Nitroglycerin (NTG), 1,2-DNG/1,3-DNGHuman Plasma20/20/20 pg/mLK2EDTA
Norethindrone (with ethinyl estradiol)Human Plasma25 pg/mLK2EDTA

NortriptylineHuman Plasma0.2 ng/mLK2EDTA
Obeticholic AcidHuman Plasma500/500/100 pg/mLK2EDTA
OctreotideRabbit Plasma0.25 ng/mLK2EDTA
OmeprazoleHuman Plasma1 ng/mLK2EDTA
OxycodoneHuman Plasma0.25 ng/mLK2EDTA
Oxycodone (with naloxone)Human Plasma50 pg/mLK2EDTA
Oxymorphone/6-HydroxyoxymorphoneHuman Plasma5/10/100 pg/mLK2EDTA
Oxymorphone/Naloxone/OxycodoneHuman Plasma50/25 pg/mLK2EDTA
OzanimodHuman Plasma4 pg/mLK2EDTA
PalbociclibHuman Plasma0.5 ng/mLK2EDTA
PalbociclibHuman Plasma0.25 ng/mLK2EDTA
PaliperidoneHuman Plasma100 pg/mLK2EDTA
PazopanibHuman Plasma100 ng/mLK2EDTA
Perindopril/ Perindoprilat/IndapamideHuman Plasma500/250/100 pg/mLK2EDTA
PhenytoinHuman Plasma40 ng/mLK2EDTA
PirfenidoneHuman Plasma100 ng/mLK2EDTA
Pramipexole (with Rasagaline)Human Plasma20 pg/mLK2EDTA
Pramipexole (with Rasagaline)Human Plasma10 pg/mLK2EDTA
PregabalinHuman Plasma25 ng/mLK2EDTA
Prilocaine (with Lidocaine)Human Plasma25 pg/mLK2EDTA
PrimidoneHuman Plasma20 ng/mLK2EDTA
ProgesteroneHuman Plasma50 pg/mLK2EDTA
ProgesteroneHuman Plasma0.2 ng/mLK2EDTA
Proguanil (with Atovaquone)Human Plasma1 ng/mLK2EDTA
Psilocybin/PsilocinHuman Plasma500/100 pg/mLK2EDTA
Pyridoxine (qualified method)Human Plasma50 pg/mLK2EDTA
Ramilril/RamiprilatHuman Plasma0.25/0.25 ng/mLK2EDTA
Rasagline (with Pramipexole)Human Plasma20 pg/mLK2EDTA
Rasagline (with Pramipexole)Human Plasma10 pg/mLK2EDTA
Regorafenib/Regorafenib-N-Oxide (M2)Human Plasma10/4 ng/mLK3EDTA
RibociclibHuman Plasma2 ng/mLK2EDTA
RisperidoneHuman Plasma0.1 ng/mLK2EDTA
RivaroxabanDog Plasma0.5 ng/mLK2EDTA
RivaroxabanHuman Plasma0.5 ng/mLK2EDTA
RizatriptanHuman Plasma0.15 ng/mLK2EDTA
RoflumilastHuman Plasma20 pg/mLK2EDTA
RopivacaineHuman Plasma1 ng/mLK2EDTA
RosuvastatinHuman Plasma100 pg/mLK2EDTA
RuxolitinibHuman Plasma2 ng/mL K2EDTA
Sacubitril (High Range) (with Valsartan)Human Plasma5 ng/mLK2EDTA
Sacubitril (Low Range) (with Valsartan)Human Plasma1 ng/mLK2EDTA
Sacubitril (Mid Range) (with Valsartan)Human Plasma1 ng/mLK2EDTA
Salicylic AcidHuman Plasma25 ng/mLSodium Fluoride/Potassium Oxalate
Salmeterol (with Fluticasone propionate)Human Plasma1 pg/mLK2EDTA
SemaglutideHuman Plasma1 ng/mLK2EDTA
SildenafilHuman Plasma0.75 ng/mLK2EDTA
Silodosin/Silodosin-β-D-GlucuronideHuman Plasma0.5/0.5 ng/mLK2EDTA
SitagliptinHuman Plasma10 ng/mLK2EDTA
SitagliptinHuman Plasma1 ng/mLK2EDTA
SofosbuvirHuman Plasma5 ng/mLK2EDTA
Solifenacin (with Tamsulosin)Human Plasma100 pg/mLK2EDTA
Sulfamethoxazole (with Trimethoprim)Human Plasma250/10 ng/mLK2EDTA
TacrolimusWhole Blood100 pg/mLK2EDTA
Tacrolimus (LR)Whole Blood50 pg/mLK2EDTA
TadalafilHuman Plasma3 ng/mLK2EDTA
Tamsulosin (with Solifenacin)Human Plasma100 pg/mLK2EDTA
TapentadolHuman Plasma0.5 ng/mLK2EDTA
TelmisartanHuman Plasma2 ng/mLK3EDTA
Tenofovir (with Dolutegravir and Lamivudine)Human Plasma5 ng/mLK2EDTA
Tenofovir AlafenamideHuman Plasma1 ng/mLK2EDTA
Tetrabenazine/α-and β-hydroxy TetrabenazineHuman Plasma20 pg/mL/0.25/0.25 ng/mLK2EDTA
ThalidomideHuman Plasma10 ng/mLK2EDTA
THC/11-OH THC (with CBD)Human Plasma100/100/100 pg/mLK2EDTA
TheophyllineHuman Plasma50 ng/mLK2EDTA
ThiorphanHuman Plasma2 ng/mLK2EDTA
Thromboxane B2Human Serum1 ng/mLN/A
Ticagrelor/Deshydroxyethoxy TicagrelorHuman Plasma5/2.5 ng/mLK2EDTA
TiotropiumHuman Plasma0.5 pg/mLK2EDTA
Tramadol/DexketoprofenHuman Plasma3/30 ng/mLK2EDTA
Triamcinolone AcetonideHuman Plasma10 pg/mLK2EDTA
Trientine/N1-AcetyitriethyienetetramineHuman Plasma10 ng/mLK2EDTA
Trimethoprim (with sulfamethoxazole)Human Plasma10 ng/mLK2EDTA
Ulipristal AcetateHuman Plasma0.25 ng/mLK2EDTA
Ulipristal Acetate/N-Desmethyl Ulipristal AcetateHuman Plasma1/0.5 ng/mLK2EDTA
ValsartanHuman Plasma80 ng/mLK2EDTA
Valsartan (with hydrochlorothiazide)Human Plasma20 ng/mLK2EDTA
Valsartan (with Sacubitril) High RangeHuman Plasma10 ng/mLK2EDTA
Valsartan (with Sacubitril) Low RangeHuman Plasma1 ng/mLK2EDTA
Valsartan (with Sacubitril) Med RangeHuman Plasma2.5 ng/mLK2EDTA
VancomycinDog Plasma0.5 µg/mLK2EDTA
Valproic AcidHuman Plasma0.5 µg/mLK2EDTA
VareniclineHuman Plasma100 pg/mLK2EDTA
VigabatrinHuman Plasma0.25 µg/mLK2EDTA
VildagliptinHuman Plasma2 ng/mLK2EDTA
VoriconazoleHuman Plasma10 ng/mLK2EDTA

List of Methods in Development and/or Validation

COMPOUNDSMATRIXLLOQANTICOAGULANT
ApremilastHuman Plasma1 ng/mLK2EDTA
BosentanHuman Plasma20 ng/mLK2EDTA
ChlortalidoneHuman Plasma2 ng/mLK2EDTA
CariprazineHuman Plasma10 pg/mLK2EDTA
DiltiazemHuman Plasma3 ng/mLK2EDTA
Doxepin/Nordoxepin (Low Range)Human Plasma5/5 pg/mLK2EDTA
Fesoterodine/5-HMTHuman Plasma1/10 pg/mLK2EDTA
5-FlurouracilHuman Plasma1 ng/mLK2EDTA
FlucytosineHuman Plasma50 ng/mLK2EDTA
Hydrochlorothiazide (with Valsartan)Human Plasma1 ng/mLK2EDTA
HydromorphoneHuman Plasma50 pg/mLK2EDTA
Levodopa/CarbidopaHuman Plasma10/1 ng/mLK2EDTA
LinagliptinHuman Plasma0.05 ng/mLK2EDTA
6-MercaptopurineHuman Plasma300 pg/mLK2EDTA
NaproxenHuman Plasma1 µg/mLK2EDTA
PrazosinHuman Plasma0.2 ng/mLK2EDTA
RitonavirHuman Plasma10 ng/mLK2EDTA
RivastigmineHuman Plasma0.1 ng/mLK2EDTA
TeduglutideHuman Plasma0.2 ng/mLK2EDTA
TestosteroneHuman Plasma0.05 ng/mLK2EDTA
Venlafaxine/O-Desmethyl Venlafaxine *Human Plasma0.5/1 ng/mLK2EDTA
*Method developed and waiting to be validated

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