The efficient and timely enrollment of study participants is key to the success of clinical trials. However, the process of clinical trial recruitment has consistently been associated with challenges. For example, up to 85% of clinical trials face difficulties to...
Understanding the Vasoconstriction Assay for Topical Corticosteroids In general, traditional pharmacokinetic (PK) endpoint studies, comparing the rate and extent of absorption of the drug estimated from the drug concentrations in a biological fluid, are a strong...
Isomers are molecules that share the same molecular formula but have different structures. This means they contain the same number of atoms of each element, but these atoms are arranged differently. There are two main forms of isomerism: structural (or constitutional)...
In the realm of drug bioequivalence assessments and Phase 1 clinical studies, the focus has traditionally been on parameters such as Cmax (maximum concentration) and AUC (area under the concentration-time curve), owing to their critical role in evaluating therapeutic...
Clinical trials are a cornerstone of pharmaceutical development, entailing significant investment in terms of time, money, and resources. These early stage clinical trials are fraught with various risks ranging from clinical failures to regulatory issues, all of which...
Pharmacokinetics (PK) modeling has been a useful tool thorough from pre-clinic to clinical (from Phase 1 to 3) in drug development, clinical research, and therapeutic optimization for centuries. The PK model used quantitative parameters to describe the complex...
