Latest Blogs
Understanding Hepatic Impairment Pharmacokinetic Studies in Drug Development
Hepatic drug metabolism involves enzymatic reactions, including oxidation, reduction, and hydrolysis, which modify the drug q molecule and make it more water-soluble, allowing it to be excreted more easily. The main enzymes involved in drug metabolism are called...
Clinical Study Report Development: Bioequivalence-Generic Products
As a drug development sponsor, you know that creating a Clinical Study Report (CSR) is a critical part of the drug development process. It is a crucial component for regulatory agencies when determining whether to approve a drug for market. However, creating a...
Insights into Clinical Research: Effective Strategies for Study Participant Recruitment & Retention
In the world of clinical research, accelerated drug development can be a tedious process, taking over 10 years for medications to get to market. From bench to bedside, pharmaceutical companies invest millions of dollars, and delays in drug development cost thousands...
Renal Impairment Clinical Trial: A scientific approach assessing the effect of renal disease on drug’s pharmacokinetics
Renal impairment is a common comorbidity for patients because of the disease itself, toxicity of treatments, or because of other factors affecting organ function, such as increased age. Drugs are normally cleared from the human body by a number of routes, each of...
Bioanalytical Method Development: Focus on Prodrugs
As described in the "Global Pharmaceuticals Industry Analysis and Trends 2023" report by NAVADHI Market Research, the Global pharma market is expected to be worth USD 1.57 trillion by 2023. North America is expected to retain its leading position in the global pharma...
Interview preparation for a Bioanalytical Laboratory Position
Finding a job is much like finding a partner. The interview can be a stressful experience and many of us will struggle with presenting our own skills, capabilities, and talents to show us at our best. BioPharma Services Inc. (BPSI) is a full-service Contract Research...
First in Human Studies for Topically Applied Drugs
What are topical drugs? There is a long history of the use of topical drugs dating back to the 13th -14th centuries, where it was known that the extract from mandrake can be used together with lime to diffuse through the skin for treating stomach ulcers, constipation...
Whole Blood Stability Determination: Overcoming Challenges of Drug Equilibration
Before a new chemical entity (NCE) or generic pharmaceutical product reaches the market, non-clinical (GLP) and clinical studies are required to demonstrate the safety and efficacy of the product. Pharmacokinetic profiling, which measures the concentration of the drug...
Bioanalytical Method Development: Focus on Polar Compounds
Bioanalysis is a subdiscipline of analytical chemistry used in the identification and quantitative measurement of target analytes, such as drugs and their metabolites or biological molecules, in biological fluids or tissues. In the pharmaceutical industry, bioanalysis...
Risk Management in Clinical Research: Minimizing risk and ensuring data integrity
Risk management in clinical trials is the forecasting and evaluation of risk together with the identification of procedures to avoid or minimize impact. Translating that to the clinical research world of BioPharma Services, where studies are conducted with human...
SPOTLIGHT ON: Anson Wu – Deputy Study Director
I came to Canada in August 2013, to pursue my bachelor’s degree at the University of Toronto. Like many international students, I felt a little lost at first coming to a new country. I was unsure that I had made the right decision until the middle of 2014, when I...
Research Roundtable for Epilepsy: A Reflection by Dr. John Oldenhof
At the end of May, I had the pleasure of being invited to present at the Research Roundtable for Epilepsy (RRE) and discuss my experience as a parent with a child with a Developmental Epileptic Encephalopathy (DEE) from the perspective of a clinical research...
Schedule a Discovery Call
Learn how BioPharma Services can be your trusted clinical trial partner.