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Understanding the Roles of Operations and Quality in a CRO

Understanding the Roles of Operations and Quality in a CRO

In Clinical Research, as in most things in life, balance is key. An even balance between clinical operations and clinical quality assurance is essential to the success of any clinical trial, not just during the clinical conduct, but in all areas from proposal to...

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PBPK Modeling in Predicting Drug Behavior

PBPK Modeling in Predicting Drug Behavior

Physiologically-based pharmacokinetic (PBPK) is a mathematical modeling approach used in pharmacology and toxicology to predict the behavior of drugs in the body. PBPK models take into account the physiological and biochemical characteristics of the body, such as...

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What Is an ADME Study?

What Is an ADME Study?

The pharmacokinetic properties of a new chemical entity (NCE) or an investigational medicinal product (IMP) must be elucidated during clinical drug development. This includes the analysis of their absorption, distribution, metabolism, and excretion (ADME) and is...

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